Gene Information
Gene NamePRSS37
OrganismHomo sapiens (Human)
Gene Length235
Protein NamesProbable inactive serine protease 37 (Probable inactive trypsin-X2)
Target NameNA
Target TypeNA
Gene Age168 ( ENSG00000165076 )
Evolutionary StageEumetazoa
AlphaFoldDBA4D1T9
Gene CardPRSS37
Uniprot IDA4D1T9
PfamPF00089
In ASDno
Allosteric Predictionno (-1.378753814)
Ortholog in AnimalsAlpaca_ PRSS37 ( ortholog_one2one )
Alpaca_ PRSS37 ( ortholog_one2many )
Dog_ PRSS37 ( ortholog_one2one )
GuineaPig_ PRSS37 ( ortholog_one2one )
Macaque_ PRSS37 ( ortholog_one2one )
Mouse_ Prss37 ( ortholog_one2one )
Pig_ PRSS37 ( ortholog_one2one )
Rat_ Prss37 ( ortholog_one2one )
Rabbit_ PRSS37 ( ortholog_one2one )
OhnologsNA
ParalogsOVCH1, PLAT, PRSS48, PLGLB1, PLGLB2, PLG, TMPRSS12, GZMM, KLK15, PRSS27, PRSS33, PRSS57, PRSS50, KLK9
Tissuetestis
Tissue SpecificityTestis-specific (PubMed:27649891). Expressed in spermatids (at protein level) (PubMed:27649891). {ECO:0000269|PubMed:27649891}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs12669721 
Subcellular location [CC]Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:27649891}. Secreted {ECO:0000305}.
Mouse PG classificationNA
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