Gene Information
Gene NamePRSM1
OrganismHomo sapiens (Human)
Gene Length196
Protein NamesCharged multivesicular body protein 1a (Chromatin-modifying protein 1a) (CHMP1a) (Vacuolar protein sorting-associated protein 46-1) (Vps46-1) (hVps46-1)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9HD42
Gene CardCHMP1A
Uniprot IDQ9HD42
PfamPF03357
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in placenta, cultured skin fibroblasts and in osteoblast cell line MG-63. {ECO:0000269|PubMed:8863740}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.213858(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2JQ9  (NMR  2YMB  (X-ray  3.40A  4A5X  (X-ray  1.91A 
DBSNP NA 
Subcellular location [CC]Cytoplasm. Endosome membrane;
Peripheral membrane protein. Nucleus matrix. Note=The cytoplasmic form is partially membrane-associated and localizes to early endosomes. The nuclear form remains associated with the chromosome scaffold during mitosis. On overexpression, it localizes to nuclear bodies characterized by nuclease-resistant condensed chromatin.
Mouse PG classificationNA
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