| Gene Information | |
|---|---|
| Gene Name | TMPRSS9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1059 |
| Protein Names | Transmembrane protease serine 9 (EC 3.4.21.-) (Polyserase-I) (Polyserine protease 1) (Polyserase-1) [Cleaved into: Serase-1; Serase-2; Serase-3] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000178297 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q7Z410 |
| Gene Card | TMPRSS9 |
| Uniprot ID | Q7Z410 |
| Pfam | PF00057; PF00089 |
| In ASD | no |
| Allosteric Prediction | no (-0.784831773) |
| Ortholog in Animals | Alpaca_ TMPRSS9 ( ortholog_one2one ) Dog_ TMPRSS9 ( ortholog_one2one ) GuineaPig_ TMPRSS9 ( ortholog_one2one ) Macaque_ TMPRSS9 ( ortholog_one2many ) Mouse_ Tmprss9 ( ortholog_one2one ) Pig_ TMPRSS9 ( ortholog_one2one ) Rat_ Tmprss9 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TMPRSS15, TMPRSS6, HPN, TMPRSS11E, ST14, TMPRSS3, TMPRSS13, TMPRSS11D, TMPRSS2, PRSS22, TMPRSS11A, TMPRSS7, TMPRSS11B, TMPRSS5, PRSS21, PRSS41, TMPRSS11F |
| Tissue | NA |
| Tissue Specificity | Expressed in fetal human tissues, such as kidney, liver, lung and brain, and in a variety of tumor cell lines. Weakly expressed in adult tissues including skeletal muscle, liver, placenta and heart. {ECO:0000269|PubMed:12886014}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs8100709 rs891174 rs17685098 rs10153474 rs60568869 rs735911 rs7247162 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:12886014}; Single-pass type II membrane protein {ECO:0000269|PubMed:12886014}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |