Gene Information
Gene NameHTRA4
OrganismHomo sapiens (Human)
Gene Length476
Protein NamesSerine protease HTRA4 (EC 3.4.21.-) (High-temperature requirement factor A4)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000169495 )
Evolutionary StageCellular_organisms
AlphaFoldDBP83105
Gene CardHTRA4
Uniprot IDP83105
PfamPF00219; PF07648; PF13180; PF02163
In ASDyes
Allosteric Predictionno (-0.805653924)
Ortholog in AnimalsAlpaca_ HTRA4 ( ortholog_one2one )
Dog_ HTRA4 ( ortholog_one2one )
Macaque_ HTRA4 ( ortholog_one2one )
Mouse_ Htra4 ( ortholog_one2one )
Rat_ Htra4 ( ortholog_one2one )
Rabbit_ HTRA4 ( ortholog_one2one )
OhnologsHTRA1, HTRA2, HTRA3
ParalogsHTRA2, HTRA1, HTRA3
Tissueplacenta
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Secreted {ECO:0000250}.
Mouse PG classificationNA
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