Gene Information
Gene NameMYOZ2
OrganismHomo sapiens (Human)
Gene Length264
Protein NamesMyozenin-2 (Calsarcin-1) (FATZ-related protein 2)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000172399 )
Evolutionary StageVertebrata
AlphaFoldDBQ9NPC6
Gene CardMYOZ2
Uniprot IDQ9NPC6
PfamPF05556
In ASDno
Allosteric Predictionno (-1.091742416)
Ortholog in AnimalsAlpaca_ MYOZ2 ( ortholog_one2one )
Dog_ MYOZ2 ( ortholog_one2one )
GuineaPig_ MYOZ2 ( ortholog_one2one )
Macaque_ MYOZ2 ( ortholog_one2one )
Mouse_ Myoz2 ( ortholog_one2one )
Pig_ MYOZ2 ( ortholog_one2one )
Rat_ Myoz2 ( ortholog_one2one )
Rabbit_ MYOZ2 ( ortholog_one2one )
OhnologsNA
ParalogsMYOZ3, MYOZ1
Tissueheart, left.atrium, left.ventricle, pulmonary.valve, atrium
Tissue SpecificityExpressed specifically in heart and skeletal muscle. {ECO:0000269|PubMed:11114196, ECO:0000269|PubMed:11161785}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs199476398  rs140126678 
Subcellular location [CC]Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}. Note=Colocalizes with ACTN1 and PPP3CA at the Z-line of heart and skeletal muscle. {ECO:0000250}.
Mouse PG classificationHPG
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