| Gene Information | |
|---|---|
| Gene Name | PRR5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 388 |
| Protein Names | Proline-rich protein 5 (Protein observed with Rictor-1) (Protor-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000186654 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P85299 |
| Gene Card | PRR5 |
| Uniprot ID | P85299 |
| Pfam | PF08539 |
| In ASD | no |
| Allosteric Prediction | no (-0.663371976) |
| Ortholog in Animals | Alpaca_ PRR5 ( ortholog_one2one ) Dog_ PRR5 ( ortholog_one2one ) GuineaPig_ PRR5 ( ortholog_one2one ) Macaque_ PRR5 ( ortholog_one2one ) Mouse_ Prr5 ( ortholog_one2one ) Pig_ PRR5 ( ortholog_one2one ) Rat_ Prr5 ( ortholog_one2one ) |
| Ohnologs | ARHGAP1 |
| Paralogs | PRR5L |
| Tissue | NA |
| Tissue Specificity | Most abundant in kidney and liver. Also highly expressed in brain, spleen, testis and placenta. Overexpressed in several colorectal tumors. {ECO:0000269|PubMed:15718101, ECO:0000269|PubMed:17599906}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs36082900 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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