| Gene Information | |
|---|---|
| Gene Name | DRNI |
| Organism | Homo sapiens (Human) |
| Gene Length | 282 |
| Protein Names | Deoxyribonuclease-1 (EC 3.1.21.1) (Deoxyribonuclease I) (DNase I) (Dornase alfa) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P24855 |
| Gene Card | DNASE1 |
| Uniprot ID | P24855 |
| Pfam | PF03372 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Principally in tissues of the digestive system. Highest levels found in urine, but also relatively abundant in semen and saliva. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4AWN (X-ray 1.95A ) |
| DBSNP | rs8176927 rs77254040 rs8176928 rs530214101 rs8176919 rs1799891 rs148373909 rs8176940 rs1053874 rs8176939 rs8176924 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:2277032}. Zymogen granule {ECO:0000305}. Nucleus envelope. Note=Secretory protein, stored in zymogen granules and found in the nuclear envelope. |
| Mouse PG classification | NA |
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