| Gene Information | |
|---|---|
| Gene Name | PRR3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 549 |
| Protein Names | Nectin-3 (CDw113) (Nectin cell adhesion molecule 3) (Poliovirus receptor-related protein 3) (CD antigen CD113) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000204576 ) 3 ( ENSG00000206491 ) 3 ( ENSG00000223766 ) 3 ( ENSG00000223887 ) 3 ( ENSG00000228186 ) 3 ( ENSG00000229202 ) 3 ( ENSG00000233564 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9NQS3 |
| Gene Card | NECTIN3 |
| Uniprot ID | Q9NQS3 |
| Pfam | PF08205; PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-1.453754843) |
| Ortholog in Animals | Alpaca_ PRR3 ( ortholog_one2one ) Dog_ PRR3 ( ortholog_one2many ) GuineaPig_ PRR3 ( ortholog_one2one ) Macaque_ PRR3 ( ortholog_one2one ) Mouse_ Prr3 ( ortholog_one2one ) Pig_ PRR3 ( ortholog_one2one ) Rat_ Prr3 ( ortholog_one2one ) Rabbit_ PRR3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PPP1R10, ZC3H18 |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in testis and placenta as well as in many cell lines, including epithelial cell lines. {ECO:0000269|PubMed:11024295}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4FOM (X-ray 3.93A ) |
| DBSNP | rs15611 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:26038560}; Single-pass membrane protein {ECO:0000255}. Postsynaptic cell membrane {ECO:0000250}. |
| Mouse PG classification | NA |
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