| Gene Information | |
|---|---|
| Gene Name | DPYSL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 572 |
| Protein Names | Dihydropyrimidinase-related protein 1 (DRP-1) (Collapsin response mediator protein 1) (CRMP-1) (Inactive dihydropyrimidinase) (Unc-33-like phosphoprotein 3) (ULIP-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q14194 |
| Gene Card | CRMP1 |
| Uniprot ID | Q14194 |
| Pfam | PF01979 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Brain. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4B3Z (X-ray 3.05A ) |
| DBSNP | rs34611001 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11562390}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:11562390}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:11562390}. Cell projection, growth cone {ECO:0000250|UniProtKB:P97427}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P97427}. Perikaryon {ECO:0000250|UniProtKB:P97427}. Note=Associated with centrosomes and the mitotic spindle during metaphase (PubMed:11562390). Colocalizes with FLNA and tubulin in the central region of DRG neuron growth cone (By similarity). Following SEMA3A stimulation of DRG neurons, colocalizes with F-actin (By similarity). {ECO:0000250|UniProtKB:P97427, ECO:0000269|PubMed:11562390}. |
| Mouse PG classification | NA |
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