| Gene Information | |
|---|---|
| Gene Name | FABGL |
| Organism | Homo sapiens (Human) |
| Gene Length | 261 |
| Protein Names | (3R)-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12) (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (HSD17B8) (3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit) (KAR alpha subunit) (3-oxoacyl-[acyl-carrier-protein] reductase) (Estradiol 17-beta-dehydrogenase 8) (EC 1.1.1.62) (Protein Ke6) (Ke6) (Short chain dehydrogenase/reductase family 30C member 1) (Testosterone 17-beta-dehydrogenase 8) (EC 1.1.1.239) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q92506 |
| Gene Card | HSD17B8 |
| Uniprot ID | Q92506 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed, particularly abundant in prostate, placenta and kidney (PubMed:17978863). Expressed at protein level in various tissues like brain, cerebellum, heart, lung, kidney, ovary, testis, adrenals and prostate (PubMed:30508570). {ECO:0000269|PubMed:17978863, ECO:0000269|PubMed:30508570}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2PD6 (X-ray 2.00A ) 4CQL (X-ray 2.85A ) 4CQM (X-ray 2.34A ) |
| DBSNP | rs34491699 |
| Subcellular location [CC] | Mitochondrion matrix {ECO:0000269|PubMed:19571038}. |
| Mouse PG classification | NA |
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