| Gene Information | |
|---|---|
| Gene Name | PRPF6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 941 |
| Protein Names | Pre-mRNA-processing factor 6 (Androgen receptor N-terminal domain-transactivating protein 1) (ANT-1) (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000101161 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O94906 |
| Gene Card | PRPF6 |
| Uniprot ID | O94906 |
| Pfam | PF06424; PF13181 |
| In ASD | no |
| Allosteric Prediction | no (-0.346383532) |
| Ortholog in Animals | Alpaca_ PRPF6 ( ortholog_one2one ) Dog_ PRPF6 ( ortholog_one2one ) GuineaPig_ PRPF6 ( ortholog_one2one ) Macaque_ PRPF6 ( ortholog_one2one ) Mouse_ Prpf6 ( ortholog_one2one ) Pig_ PRPF6 ( ortholog_one2one ) Rat_ Prpf6 ( ortholog_one2one ) Rabbit_ PRPF6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CRNKL1, XAB2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:12039962}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3JCR (EM 7.00A ) 5O9Z (EM 4.50A ) 6AH0 (EM 5.70A ) 6AHD (EM 3.80A ) 6QW6 (EM 2.92A ) 6QX9 (EM 3.28A ) |
| DBSNP | rs1433048453 rs387907100 |
| Subcellular location [CC] | Nucleus, nucleoplasm {ECO:0000269|PubMed:10561546, ECO:0000269|PubMed:26912367, ECO:0000269|PubMed:28781166, ECO:0000269|PubMed:34023904}. Nucleus speckle {ECO:0000269|PubMed:21549338}. Note=Localized in splicing speckles. {ECO:0000269|PubMed:21549338}. |
| Mouse PG classification | LPG |
| click here to return to the previous page | |