| Gene Information | |
|---|---|
| Gene Name | PRPF4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 522 |
| Protein Names | U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000136875 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O43172 |
| Gene Card | PRPF4 |
| Uniprot ID | O43172 |
| Pfam | PF08799; PF00400 |
| In ASD | no |
| Allosteric Prediction | no (-0.953311115) |
| Ortholog in Animals | Alpaca_ PRPF4 ( ortholog_one2one ) Dog_ PRPF4 ( ortholog_one2one ) Macaque_ PRPF4 ( ortholog_one2one ) Mouse_ Prpf4 ( ortholog_one2one ) Pig_ PRPF4 ( ortholog_one2one ) Rat_ Prpf4 ( ortholog_one2one ) Rabbit_ PRPF4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.197631(Rat);0.145278(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1MZW (X-ray 2.00A ) 3JCR (EM 7.00A ) 5O9Z (EM 4.50A ) 6AH0 (EM 5.70A ) 6AHD (EM 3.80A ) 6QW6 (EM 2.92A ) 6QX9 (EM 3.28A ) |
| DBSNP | rs41296057 rs587777599 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:25383878, ECO:0000269|PubMed:26912367, ECO:0000269|PubMed:28781166, ECO:0000269|PubMed:9257651, ECO:0000269|PubMed:9328476, ECO:0000269|PubMed:9404889}. Nucleus speckle {ECO:0000305}. |
| Mouse PG classification | NA |
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