| Gene Information | |
|---|---|
| Gene Name | PIK3R6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 754 |
| Protein Names | Phosphoinositide 3-kinase regulatory subunit 6 (Phosphoinositide 3-kinase gamma adapter protein of 87 kDa) (p84 PI3K adapter protein) (p84 PIKAP) (p87 PI3K adapter protein) (p87PIKAP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000276231 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q5UE93 |
| Gene Card | PIK3R6 |
| Uniprot ID | Q5UE93 |
| Pfam | PF10486 |
| In ASD | no |
| Allosteric Prediction | yes (0.734337056) |
| Ortholog in Animals | Alpaca_ PIK3R6 ( ortholog_one2one ) Dog_ PIK3R6 ( ortholog_one2one ) GuineaPig_ PIK3R6 ( ortholog_one2one ) Macaque_ PIK3R6 ( ortholog_one2one ) Mouse_ Pik3r6 ( ortholog_one2one ) Pig_ PIK3R6 ( ortholog_one2one ) Rat_ Pik3r6 ( ortholog_one2one ) Rabbit_ PIK3R6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PIK3R5 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q3U6Q4}. Cell membrane {ECO:0000250|UniProtKB:Q3U6Q4}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q3U6Q4}. Note=Translocated to the plasma membrane in a Ras-dependent manner. {ECO:0000250|UniProtKB:Q3U6Q4}. |
| Mouse PG classification | NA |
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