| Gene Information | |
|---|---|
| Gene Name | PRP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 683 |
| Protein Names | U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) (hPrp3) (U4/U6 snRNP 90 kDa protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O43395 |
| Gene Card | PRPF3 |
| Uniprot ID | O43395 |
| Pfam | PF06544; PF08572; PF01480 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in retina, liver, kidney and blood. Detected at lower levels in heart and brain. {ECO:0000269|PubMed:11773002}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.140848(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1X4Q (NMR - ) 3JCR (EM 7.00A ) 5O9Z (EM 4.50A ) 6AH0 (EM 5.70A ) 6AHD (EM 3.80A ) 6QW6 (EM 2.92A ) 6QX9 (EM 3.28A ) |
| DBSNP | rs12736964 rs121434242 rs121434241 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:17932117, ECO:0000269|PubMed:26912367, ECO:0000269|PubMed:28781166, ECO:0000269|PubMed:9328476, ECO:0000269|PubMed:9404889}. Nucleus speckle. |
| Mouse PG classification | NA |
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