| Gene Information | |
|---|---|
| Gene Name | PICK1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 415 |
| Protein Names | PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000100151 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9NRD5 |
| Gene Card | PICK1 |
| Uniprot ID | Q9NRD5 |
| Pfam | PF06456; PF00595 |
| In ASD | no |
| Allosteric Prediction | no (-0.108597391) |
| Ortholog in Animals | Alpaca_ PICK1 ( ortholog_one2one ) Dog_ PICK1 ( ortholog_one2one ) GuineaPig_ PICK1 ( ortholog_one2one ) Macaque_ PICK1 ( ortholog_one2one ) Mouse_ Pick1 ( ortholog_one2one ) Pig_ PICK1 ( ortholog_one2one ) Rat_ Pick1 ( ortholog_one2one ) Rabbit_ PICK1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ARFIP2, ARFIP1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.001823(Rat);0.017391(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2GZV (X-ray 1.12A ) 6AR4 (X-ray 1.69A ) 6BJN (X-ray 2.43A ) 6BJO (X-ray 1.75A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, perinuclear region. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Postsynaptic density {ECO:0000250}. Synapse, synaptosome {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Also membrane-associated, present at excitatory synapses. {ECO:0000250}. |
| Mouse PG classification | NA |
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