| Gene Information | |
|---|---|
| Gene Name | PROKR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 384 |
| Protein Names | Prokineticin receptor 2 (PK-R2) (G-protein coupled receptor 73-like 1) (G-protein coupled receptor I5E) (GPR73b) (GPRg2) |
| Target Name | prokineticin receptor 2 |
| Target Type | Literature-reported target |
| Gene Age | 544 ( ENSG00000101292 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8NFJ6 |
| Gene Card | PROKR2 |
| Uniprot ID | Q8NFJ6 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (0.528689032) |
| Ortholog in Animals | Alpaca_ PROKR2 ( ortholog_one2one ) Dog_ PROKR2 ( ortholog_one2one ) GuineaPig_ PROKR2 ( ortholog_one2one ) Macaque_ PROKR2 ( ortholog_one2one ) Mouse_ Prokr2 ( ortholog_one2one ) Pig_ PROKR2 ( ortholog_one2one ) Rat_ Prokr2 ( ortholog_one2one ) Rabbit_ PROKR2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PROKR1, TACR2, OR9A2, NPY1R, MTNR1B, OR11H6, OR11H7, OR11H4, OR9A1P, OR9G1, NPY2R, MTNR1A, GPR50, GPR75, OR11G2, MCHR2, MCHR1, GPR19, OR11A1, TACR1, TACR3, OR11H2, OR11H12, OR11H1, GPR83, GPR88, PRLHR, OR51F1, OR10X1, NPY5R, OR9A4, NPY4R2, NPY4R |
| Tissue | NA |
| Tissue Specificity | Expressed in the ileocecum, thyroid gland, pituitary gland, salivary gland, adrenal gland, testis, ovary and brain. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs141090506 rs74315418 rs202203360 rs138672528 rs368732206 rs751875578 rs74315416 rs201835496 rs376239580 rs200755554 rs74315417 rs376142095 rs78861628 rs149992595 rs74315419 rs117106081 rs371564610 rs755562438 rs375036628 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:18826963}; Multi-pass membrane protein. |
| Mouse PG classification | LPG |
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