| Gene Information | |
|---|---|
| Gene Name | LOXL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 574 |
| Protein Names | Lysyl oxidase homolog 1 (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (LOL) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000129038 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q08397 |
| Gene Card | LOXL1 |
| Uniprot ID | Q08397 |
| Pfam | PF01186 |
| In ASD | no |
| Allosteric Prediction | no (-0.129887163) |
| Ortholog in Animals | Alpaca_ LOXL1 ( ortholog_one2one ) Dog_ LOXL1 ( ortholog_one2one ) GuineaPig_ LOXL1 ( ortholog_one2one ) Macaque_ LOXL1 ( ortholog_one2one ) Mouse_ Loxl1 ( ortholog_one2one ) Pig_ LOXL1 ( ortholog_one2one ) Rat_ Loxl1 ( ortholog_one2one ) Rabbit_ LOXL1 ( ortholog_one2one ) |
| Ohnologs | LOX |
| Paralogs | CD6, LOX, SSC4D, SSC5D, LGALS3BP, LOXL4, SCART1, CD163, PRSS12, DMBT1, LOXL3, CD5, CD5L, LOXL2, CD163L1 |
| Tissue | NA |
| Tissue Specificity | Expressed in ocular tissues including the iris, ciliary body, lens and optic nerve. Not detected in the retina. {ECO:0000269|PubMed:18037624}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1048661 rs3825942 |
| Subcellular location [CC] | Secreted, extracellular space {ECO:0000305}. |
| Mouse PG classification | LPG |
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