| Gene Information | |
|---|---|
| Gene Name | PTPA |
| Organism | Homo sapiens (Human) |
| Gene Length | 358 |
| Protein Names | Serine/threonine-protein phosphatase 2A activator (EC 5.2.1.8) (PP2A, subunit B', PR53 isoform) (Phosphotyrosyl phosphatase activator) (PTPA) (Serine/threonine-protein phosphatase 2A regulatory subunit 4) (Serine/threonine-protein phosphatase 2A regulatory subunit B') |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000119383 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q15257 |
| Gene Card | PTPA |
| Uniprot ID | Q15257 |
| Pfam | PF03095 |
| In ASD | no |
| Allosteric Prediction | yes (0.855925373) |
| Ortholog in Animals | Alpaca_ PTPA ( ortholog_one2many ) Dog_ PTPA ( ortholog_one2one ) GuineaPig_ PTPA ( ortholog_one2one ) Macaque_ PTPA ( ortholog_one2one ) Mouse_ Ptpa ( ortholog_one2one ) Pig_ PTPA ( ortholog_one2one ) Rat_ Ptpa ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002882(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2G62 (X-ray 1.60A ) 2HV6 (X-ray 1.90A ) 2HV7 (X-ray 2.50A ) 2IXM (X-ray 1.50A ) 4LAC (X-ray 2.82A ) 4NY3 (X-ray 1.80A ) |
| DBSNP | rs17481693 rs4836639 rs2480452 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17333320}. Nucleus {ECO:0000269|PubMed:17333320}. |
| Mouse PG classification | NA |
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