| Gene Information | |
|---|---|
| Gene Name | DUSP19 |
| Organism | Homo sapiens (Human) |
| Gene Length | 217 |
| Protein Names | Dual specificity protein phosphatase 19 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase TS-DSP1) (Low molecular weight dual specificity phosphatase 3) (LMW-DSP3) (Protein phosphatase SKRP1) (Stress-activated protein kinase pathway-regulating phosphatase 1) (SAPK pathway-regulating phosphatase 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000162999 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8WTR2 |
| Gene Card | DUSP19 |
| Uniprot ID | Q8WTR2 |
| Pfam | PF00782 |
| In ASD | no |
| Allosteric Prediction | no (-0.789979513) |
| Ortholog in Animals | Alpaca_ DUSP19 ( ortholog_one2one ) Dog_ DUSP19 ( ortholog_one2one ) GuineaPig_ DUSP19 ( ortholog_one2one ) Macaque_ DUSP19 ( ortholog_one2one ) Mouse_ Dusp19 ( ortholog_one2one ) Pig_ DUSP19 ( ortholog_one2one ) Rat_ Dusp19 ( ortholog_one2one ) Rabbit_ DUSP19 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DUSP6, DUSP4, DUSP12, DUSP10, STYXL2, SSH3, DUSP1, KASH5, SSH1, DUSP29, DUSP16, DUSP21, DUSP2, DUSP8, DUSP13, EPM2A, DUSP7, DUSP26, STYX, SSH2, PTPMT1, DUSP22, DUSP18, DUSP15, DUSP14, DUSP28, STYXL1, DUSP5, DUSP9, DUSP3 |
| Tissue | NA |
| Tissue Specificity | Expressed in the heart, lung, liver, and pancreas. The expression level in the pancreas is the highest. {ECO:0000269|PubMed:12479873}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3S4E (X-ray 1.26A ) 4D3P (X-ray 1.27A ) 4D3Q (X-ray 1.64A ) 4D3R (X-ray 1.67A ) |
| DBSNP | rs16823987 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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