| Gene Information | |
|---|---|
| Gene Name | TXNDC11 |
| Organism | Homo sapiens (Human) |
| Gene Length | 985 |
| Protein Names | Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000153066 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q6PKC3 |
| Gene Card | TXNDC11 |
| Uniprot ID | Q6PKC3 |
| Pfam | PF00085 |
| In ASD | no |
| Allosteric Prediction | no (-1.407893594) |
| Ortholog in Animals | Alpaca_ TXNDC11 ( ortholog_one2one ) Dog_ TXNDC11 ( ortholog_one2one ) GuineaPig_ TXNDC11 ( ortholog_one2one ) Macaque_ TXNDC11 ( ortholog_one2one ) Mouse_ Txndc11 ( ortholog_one2one ) Pig_ TXNDC11 ( ortholog_one2one ) Rat_ Txndc11 ( ortholog_one2many ) Rabbit_ TXNDC11 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ERP27, PDIA6, TMX1, TMX4, TMX3, PDILT, ERP44, PDIA2, PDIA3, PDIA4, PDIA5, P4HB, TXNDC5 |
| Tissue | NA |
| Tissue Specificity | Widely expressed at low level. Expressed at higher level in thyroid and prostate. {ECO:0000269|PubMed:15561711}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.028571(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3190321 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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