| Gene Information | |
|---|---|
| Gene Name | COX6A2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 97 |
| Protein Names | Cytochrome c oxidase subunit 6A2, mitochondrial (Cytochrome c oxidase polypeptide VIa-heart) (COXVIAH) (Cytochrome c oxidase subunit VIA-muscle) (COX VIa-M) |
| Target Name | cytochrome c oxidase subunit 6a2, mitochondrial |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000156885 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q02221 |
| Gene Card | COX6A2 |
| Uniprot ID | Q02221 |
| Pfam | PF02046 |
| In ASD | no |
| Allosteric Prediction | no (-0.997486247) |
| Ortholog in Animals | Alpaca_ COX6A2 ( ortholog_one2one ) Dog_ COX6A2 ( ortholog_one2one ) GuineaPig_ COX6A2 ( ortholog_one2one ) Macaque_ COX6A2 ( ortholog_one2one ) Mouse_ Cox6a2 ( ortholog_one2one ) Pig_ COX6A2 ( ortholog_one2one ) Rat_ Cox6a2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | COX6A1 |
| Tissue | heart, skeletal.muscle, atrium, left.ventricle |
| Tissue Specificity | Expressed specifically in heart and muscle (PubMed:31155743). Not detected in brain, colon, spleen, kidney, liver, lung and pancreas (PubMed:31155743). {ECO:0000269|PubMed:1327966, ECO:0000269|PubMed:31155743}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.779562(Rat);0.037500(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1597176845 rs1275864234 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000250|UniProtKB:P07471}; Single-pass membrane protein {ECO:0000250|UniProtKB:P07471}. |
| Mouse PG classification | NA |
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