Gene Information
Gene NamePRNP
OrganismHomo sapiens (Human)
Gene Length73
Protein NamesAlternative prion protein (AltPrP)
Target Namealternative prion protein
Target TypeNA
Gene Age3 ( ENSG00000171867 )
Evolutionary StageVertebrata
AlphaFoldDBF7VJQ1
Gene CardPRNP
Uniprot IDF7VJQ1
PfamNA
In ASDno
Allosteric Predictionyes (0.090052791)
Ortholog in AnimalsAlpaca_ PRNP ( ortholog_one2one )
Dog_ PRNP ( ortholog_one2one )
GuineaPig_ PRNP ( ortholog_one2one )
Macaque_ PRNP ( ortholog_one2one )
Mouse_ Prnp ( ortholog_one2one )
Pig_ PRNP ( ortholog_one2one )
Rat_ Prnp ( ortholog_one2one )
Rabbit_ PRNP ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityDetected in brain homogenate, primary neurons, and peripheral blood mononuclear cells (at protein level). {ECO:0000269|PubMed:21478263}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Mitochondrion outer membrane {ECO:0000269|PubMed:21478263};
Single-pass membrane protein {ECO:0000269|PubMed:21478263}.
Mouse PG classificationNA
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