| Gene Information | |
|---|---|
| Gene Name | PRNP |
| Organism | Homo sapiens (Human) |
| Gene Length | 73 |
| Protein Names | Alternative prion protein (AltPrP) |
| Target Name | major prion protein |
| Target Type | NA |
| Gene Age | 3 ( ENSG00000171867 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | F7VJQ1 |
| Gene Card | PRNP |
| Uniprot ID | F7VJQ1 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | yes (0.090052791) |
| Ortholog in Animals | Alpaca_ PRNP ( ortholog_one2one ) Dog_ PRNP ( ortholog_one2one ) GuineaPig_ PRNP ( ortholog_one2one ) Macaque_ PRNP ( ortholog_one2one ) Mouse_ Prnp ( ortholog_one2one ) Pig_ PRNP ( ortholog_one2one ) Rat_ Prnp ( ortholog_one2one ) Rabbit_ PRNP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in brain homogenate, primary neurons, and peripheral blood mononuclear cells (at protein level). {ECO:0000269|PubMed:21478263}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion outer membrane {ECO:0000269|PubMed:21478263}; Single-pass membrane protein {ECO:0000269|PubMed:21478263}. |
| Mouse PG classification | NA |
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