| Gene Information | |
|---|---|
| Gene Name | ASZ1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 475 |
| Protein Names | Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Ankyrin-like protein 1) (Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000154438 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8WWH4 |
| Gene Card | ASZ1 |
| Uniprot ID | Q8WWH4 |
| Pfam | PF00023; PF12796; PF07647 |
| In ASD | no |
| Allosteric Prediction | no (-0.905091799) |
| Ortholog in Animals | Alpaca_ ASZ1 ( ortholog_one2one ) Dog_ ASZ1 ( ortholog_one2one ) GuineaPig_ ASZ1 ( ortholog_one2one ) Macaque_ ASZ1 ( ortholog_one2one ) Mouse_ Asz1 ( ortholog_one2one ) Pig_ ASZ1 ( ortholog_one2one ) Rat_ Asz1 ( ortholog_one2one ) Rabbit_ ASZ1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ANKRD34C |
| Tissue | testis |
| Tissue Specificity | Expressed exclusively in the testis and ovary and at higher levels in the adult testis compared with the adult ovary. {ECO:0000269|PubMed:12040005}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1029396 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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