| Gene Information | |
|---|---|
| Gene Name | PRMT3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 531 |
| Protein Names | Protein arginine N-methyltransferase 3 (EC 2.1.1.319) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3) |
| Target Name | protein arginine n-methyltransferase 3 |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000185238 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O60678 |
| Gene Card | PRMT3 |
| Uniprot ID | O60678 |
| Pfam | NA |
| In ASD | yes |
| Allosteric Prediction | yes (0.999895675) |
| Ortholog in Animals | Alpaca_ PRMT3 ( ortholog_one2one ) Dog_ PRMT3 ( ortholog_one2one ) GuineaPig_ PRMT3 ( ortholog_one2one ) Macaque_ PRMT3 ( ortholog_one2one ) Mouse_ Prmt3 ( ortholog_one2one ) Pig_ PRMT3 ( ortholog_one2one ) Rat_ Prmt3 ( ortholog_one2one ) Rabbit_ PRMT3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PRMT2, PRMT7, PRMT9, PRMT1, CARM1, PRMT6, PRMT8 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.002101(Rat);0.018182(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2FYT (X-ray 2.00A ) 3SMQ (X-ray 2.00A ) 4HSG (X-ray 2.30A ) 4QQN (X-ray 2.08A ) 4RYL (X-ray 2.10A ) |
| DBSNP | rs3758805 rs11025585 rs6483700 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:9642256}. |
| Mouse PG classification | NA |
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