Gene Information | |
---|---|
Gene Name | PRL3 |
Organism | Homo sapiens (Human) |
Gene Length | 173 |
Protein Names | Protein tyrosine phosphatase type IVA 3 (EC 3.1.3.48) (PRL-R) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) |
Target Name | NA |
Target Type | NA |
Gene Age | NA |
Evolutionary Stage | NA |
AlphaFoldDB | O75365 |
Gene Card | PTP4A3 |
Uniprot ID | O75365 |
Pfam | PF00102 |
In ASD | yes |
Allosteric Prediction | NA |
Ortholog in Animals | NA |
Ohnologs | NA |
Paralogs | NA |
Tissue | NA |
Tissue Specificity | Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis. {ECO:0000269|PubMed:11355880}. |
Pharmacological Animal Models | NA |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
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Gene Ontology (molecular function) |
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PDB | 1R6H (NMR - ) 1V3A (NMR - ) 2MBC (NMR - ) 5TSR (X-ray 3.19A ) |
DBSNP | NA |
Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:12782572}. Early endosome {ECO:0000269|PubMed:12782572}. |
Mouse PG classification | NA |
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