| Gene Information | |
|---|---|
| Gene Name | BCAP31 |
| Organism | Homo sapiens (Human) |
| Gene Length | 246 |
| Protein Names | B-cell receptor-associated protein 31 (BCR-associated protein 31) (Bap31) (6C6-AG tumor-associated antigen) (Protein CDM) (p28) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000185825 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P51572 |
| Gene Card | BCAP31 |
| Uniprot ID | P51572 |
| Pfam | PF05529; PF18035 |
| In ASD | no |
| Allosteric Prediction | no (-0.382859578) |
| Ortholog in Animals | Alpaca_ BCAP31 ( ortholog_one2one ) Dog_ BCAP31 ( ortholog_one2one ) GuineaPig_ BCAP31 ( ortholog_one2one ) Macaque_ BCAP31 ( ortholog_one2one ) Mouse_ Bcap31 ( ortholog_one2one ) Pig_ BCAP31 ( ortholog_one2one ) Rat_ Bcap31 ( ortholog_one2one ) Rabbit_ BCAP31 ( ortholog_one2one ) |
| Ohnologs | BCAP29 |
| Paralogs | BCAP29 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Highly expressed in neurons and discrete endocrine cells. {ECO:0000269|PubMed:11561007}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);0.050000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4JZL (X-ray 2.20A ) 4JZP (X-ray 2.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:31206022, ECO:0000269|PubMed:9334338, ECO:0000269|PubMed:9396746}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:11042173, ECO:0000269|PubMed:9396746}; Multi-pass membrane protein {ECO:0000255}. Note=May shuttle between the ER and the intermediate compartment/cis-Golgi complex (PubMed:9396746). Associates with the mitochondria-associated endoplasmic reticulum membrane via interaction with TOMM40 (PubMed:31206022). {ECO:0000269|PubMed:31206022, ECO:0000269|PubMed:9396746}. |
| Mouse PG classification | NA |
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