Gene Information
Gene NamePCIF1
OrganismHomo sapiens (Human)
Gene Length704
Protein NamesmRNA (2'-O-methyladenosine-N(6)-)-methyltransferase (EC 2.1.1.62) (Cap-specific adenosine methyltransferase) (CAPAM) (hCAPAM) (Phosphorylated CTD-interacting factor 1) (hPCIF1) (Protein phosphatase 1 regulatory subunit 121)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000100982 )
Evolutionary StageEukaryota
AlphaFoldDBQ9H4Z3
Gene CardPCIF1
Uniprot IDQ9H4Z3
PfamPF12237; PF00397
In ASDno
Allosteric Predictionno (-1.320377113)
Ortholog in AnimalsAlpaca_ PCIF1 ( ortholog_one2one )
Dog_ PCIF1 ( ortholog_one2one )
GuineaPig_ PCIF1 ( ortholog_one2one )
Macaque_ PCIF1 ( ortholog_one2one )
Mouse_ Pcif1 ( ortholog_one2one )
Pig_ PCIF1 ( ortholog_one2one )
Rat_ Pcif1 ( ortholog_one2one )
Rabbit_ PCIF1 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityUbiquitous. {ECO:0000269|PubMed:12565871}.
Pharmacological Animal ModelsNULL(Chimpanzee);0.175650(Mouse);NULL(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2JX8  (NMR  6IRV  (X-ray  2.70A  6IRW  (X-ray  2.90A 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:12565871, ECO:0000269|PubMed:18294453, ECO:0000269|PubMed:31279659}.
Mouse PG classificationNA
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