| Gene Information | |
|---|---|
| Gene Name | SERAC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 654 |
| Protein Names | Protein SERAC1 (Serine active site-containing protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000122335 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q96JX3 |
| Gene Card | SERAC1 |
| Uniprot ID | Q96JX3 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.037425342) |
| Ortholog in Animals | Alpaca_ SERAC1 ( ortholog_one2one ) Dog_ SERAC1 ( ortholog_one2one ) GuineaPig_ SERAC1 ( ortholog_one2one ) Macaque_ SERAC1 ( ortholog_one2one ) Mouse_ Serac1 ( ortholog_one2one ) Pig_ SERAC1 ( ortholog_one2one ) Rat_ Serac1 ( ortholog_one2one ) Rabbit_ SERAC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | POP1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with predominant expression in fetal skeletal muscle and adult brain. In the brain, highest levels are found in the frontal and occipital cortices, cerebellum and hippocampus. {ECO:0000269|PubMed:22683713}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1199625391 rs201941476 rs1554261079 rs17849527 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Endoplasmic reticulum {ECO:0000269|PubMed:22683713}. Mitochondrion {ECO:0000269|PubMed:22683713}. Note=Localizes at the endoplasmic reticulum and at the endoplasmic reticulum-mitochondria interface. |
| Mouse PG classification | NA |
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