| Gene Information | |
|---|---|
| Gene Name | PRKAG3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 489 |
| Protein Names | 5'-AMP-activated protein kinase subunit gamma-3 (AMPK gamma3) (AMPK subunit gamma-3) |
| Target Name | 5'-amp-activated protein kinase |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000115592 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UGI9 |
| Gene Card | PRKAG3 |
| Uniprot ID | Q9UGI9 |
| Pfam | PF00571 |
| In ASD | no |
| Allosteric Prediction | yes (1.23682129) |
| Ortholog in Animals | Alpaca_ PRKAG3 ( ortholog_one2one ) Dog_ PRKAG3 ( ortholog_one2one ) GuineaPig_ PRKAG3 ( ortholog_one2one ) Macaque_ PRKAG3 ( ortholog_one2one ) Mouse_ Prkag3 ( ortholog_one2one ) Pig_ PRKAG3 ( ortholog_one2one ) Rat_ Prkag3 ( ortholog_one2one ) Rabbit_ PRKAG3 ( ortholog_one2one ) |
| Ohnologs | PRKAG2, PRKAG1 |
| Paralogs | PRKAG1, PRKAG2 |
| Tissue | skeletal.muscle, artery, penis |
| Tissue Specificity | Skeletal muscle, with weak expression in heart and pancreas. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.005990(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs692243 rs864622003 rs371222838 rs864622004 rs35050588 rs962993719 rs200004875 rs372752820 rs776255177 rs776263291 rs370008874 rs138130157 rs41272689 rs367916025 rs864622005 rs551272603 rs33985460 rs200750014 rs34720726 rs149508864 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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