| Gene Information | |
|---|---|
| Gene Name | PRKAG2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 569 |
| Protein Names | 5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma2) (AMPK subunit gamma-2) (H91620p) |
| Target Name | 5'-amp-activated protein kinase |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000106617 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UGJ0 |
| Gene Card | PRKAG2 |
| Uniprot ID | Q9UGJ0 |
| Pfam | PF00571 |
| In ASD | no |
| Allosteric Prediction | yes (1.264551337) |
| Ortholog in Animals | Alpaca_ PRKAG2 ( ortholog_one2one ) Dog_ PRKAG2 ( ortholog_one2one ) GuineaPig_ PRKAG2 ( ortholog_one2one ) Macaque_ PRKAG2 ( ortholog_one2one ) Mouse_ Prkag2 ( ortholog_one2one ) Pig_ PRKAG2 ( ortholog_one2one ) Rat_ Prkag2 ( ortholog_one2one ) Rabbit_ PRKAG2 ( ortholog_one2one ) |
| Ohnologs | PRKAG1, PRKAG3 |
| Paralogs | PRKAG1, PRKAG3 |
| Tissue | NA |
| Tissue Specificity | Isoform B is ubiquitously expressed except in liver and thymus. The highest level is detected in heart with abundant expression in placenta and testis. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.744621(Rat);0.232382(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3207363 rs121908987 rs121908988 rs28938173 rs121908989 rs121908990 rs121908991 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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