Gene Information
Gene NameSPINK9
OrganismHomo sapiens (Human)
Gene Length86
Protein NamesSerine protease inhibitor Kazal-type 9 (Lymphoepithelial Kazal-type-related inhibitor 2)
Target NameNA
Target TypeNA
Gene Age168 ( ENSG00000204909 )
Evolutionary StageMammalia
AlphaFoldDBQ5DT21
Gene CardSPINK9
Uniprot IDQ5DT21
PfamPF00050
In ASDno
Allosteric Predictionno (-1.385549901)
Ortholog in AnimalsAlpaca_ SPINK9 ( ortholog_one2one )
Dog_ SPINK9 ( ortholog_one2one )
Macaque_ SPINK9 ( ortholog_one2one )
Mouse_ Spink10 ( ortholog_many2many )
Mouse_ Spinkl ( ortholog_many2many )
Mouse_ Spink11 ( ortholog_many2many )
Mouse_ Gm10542 ( ortholog_many2many )
Pig_ SPINK9 ( ortholog_one2one )
Rat_ Spink10 ( ortholog_many2many )
Rabbit_ SPINK9 ( ortholog_one2one )
OhnologsNA
ParalogsSPINK7, SPINK14, SPINK8, SPINK2, SPINK13
Tissuetongue
Tissue SpecificitySkin. Highly expressed at sites of hyperkeratosis. Also detected in thymus, tonsils, testis, pancreas, liver, placenta and brain. Expressed at stratum granulosum and stratum corneum at palmar and plantar sites (at protein level). {ECO:0000269|PubMed:19190773, ECO:0000269|PubMed:19194479}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Secreted {ECO:0000305}.
Mouse PG classificationNA
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