| Gene Information | |
|---|---|
| Gene Name | TRAPPC6B |
| Organism | Homo sapiens (Human) |
| Gene Length | 158 |
| Protein Names | Trafficking protein particle complex subunit 6B (TRAPP complex subunit 6B) |
| Target Name | trafficking protein particle complex subunit 6b |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000182400 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q86SZ2 |
| Gene Card | TRAPPC6B |
| Uniprot ID | Q86SZ2 |
| Pfam | PF04051 |
| In ASD | no |
| Allosteric Prediction | no (-0.828592586) |
| Ortholog in Animals | Alpaca_ TRAPPC6B ( ortholog_one2one ) Dog_ TRAPPC6B ( ortholog_one2one ) GuineaPig_ TRAPPC6B ( ortholog_one2one ) Macaque_ TRAPPC6B ( ortholog_one2one ) Mouse_ Trappc6b ( ortholog_one2one ) Pig_ TRAPPC6B ( ortholog_one2one ) Rat_ Trappc6b ( ortholog_one2one ) Rabbit_ TRAPPC6B ( ortholog_one2one ) |
| Ohnologs | TRAPPC6A |
| Paralogs | TRAPPC6A |
| Tissue | NA |
| Tissue Specificity | Both isoforms are expressed ubiquitously (at transcript level), isoform 1 being the most predominant (PubMed:28626029). Expressed in the fetal brain and different regions of the adult brain and spinal cord (PubMed:28626029). {ECO:0000269|PubMed:28626029}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.041114(Rat);0.089237(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2BJN (X-ray 1.70A ) 2CFH (X-ray 2.30A ) 3KXC (X-ray 2.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus, cis-Golgi network {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}. |
| Mouse PG classification | NA |
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