| Gene Information | |
|---|---|
| Gene Name | PRICKLE2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 844 |
| Protein Names | Prickle-like protein 2 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000163637 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q7Z3G6 |
| Gene Card | PRICKLE2 |
| Uniprot ID | Q7Z3G6 |
| Pfam | PF00412; PF06297 |
| In ASD | no |
| Allosteric Prediction | no (-1.526079002) |
| Ortholog in Animals | Alpaca_ PRICKLE2 ( ortholog_one2one ) Dog_ PRICKLE2 ( ortholog_one2one ) GuineaPig_ PRICKLE2 ( ortholog_one2one ) Macaque_ PRICKLE2 ( ortholog_one2one ) Mouse_ Prickle2 ( ortholog_one2one ) Pig_ PRICKLE2 ( ortholog_one2one ) Rat_ Prickle2 ( ortholog_one2one ) Rabbit_ PRICKLE2 ( ortholog_one2one ) |
| Ohnologs | PRICKLE3, PRICKLE1 |
| Paralogs | PRICKLE3 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain, eye and testis. Additionally in fetal brain, adult cartilage, pancreatic islet, gastric cancer and uterus tumors. {ECO:0000269|PubMed:12525887}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs387906988 rs139747674 rs387906989 |
| Subcellular location [CC] | Nucleus membrane {ECO:0000305}. |
| Mouse PG classification | NA |
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