| Gene Information | |
|---|---|
| Gene Name | PRAM1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 670 |
| Protein Names | PML-RARA-regulated adapter molecule 1 (PRAM) (PRAM-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000133246 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q96QH2 |
| Gene Card | PRAM1 |
| Uniprot ID | Q96QH2 |
| Pfam | PF14603 |
| In ASD | no |
| Allosteric Prediction | no (-0.494993451) |
| Ortholog in Animals | Alpaca_ PRAM1 ( ortholog_one2one ) Dog_ PRAM1 ( ortholog_one2one ) GuineaPig_ PRAM1 ( ortholog_one2one ) Macaque_ PRAM1 ( ortholog_one2one ) Mouse_ Pram1 ( ortholog_one2one ) Pig_ PRAM1 ( ortholog_one2one ) Rat_ Zfp414 ( ortholog_one2one ) Rabbit_ PRAM1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FYB1, FYB2 |
| Tissue | bone.marrow, whole.blood |
| Tissue Specificity | Expressed in peripheral blood leukocytes and bone marrow. Expressed in monocytes, and to a lesser extent in granulocytes and lymphocytes. Not expressed in non hematopoietic tissues except in lung. {ECO:0000269|PubMed:11301322}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4804305 rs4239541 rs4239540 rs58466313 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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