| Gene Information | |
|---|---|
| Gene Name | PRG |
| Organism | Homo sapiens (Human) |
| Gene Length | 158 |
| Protein Names | Serglycin (Hematopoietic proteoglycan core protein) (Platelet proteoglycan core protein) (P.PG) (Secretory granule proteoglycan core protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P10124 |
| Gene Card | SRGN |
| Uniprot ID | P10124 |
| Pfam | PF04360 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2229498 |
| Subcellular location [CC] | Cytoplasmic granule {ECO:0000269|PubMed:11154222}. Cytolytic granule {ECO:0000269|PubMed:11154222}. Secreted, extracellular space {ECO:0000269|PubMed:11154222, ECO:0000269|PubMed:16870619}. Golgi apparatus {ECO:0000269|PubMed:11154222, ECO:0000269|PubMed:15136585}. Note=Found in mast cell granules and in cytoplasmic granules of cytolytic T lymphocytes from where it is secreted upon cell activation (By similarity). Secreted constitutively by endothelial cells and macrophages (PubMed:11154222). Located to Golgi apparatus during neutrophil differentiation (PubMed:15136585). {ECO:0000250|UniProtKB:P13609, ECO:0000269|PubMed:11154222, ECO:0000269|PubMed:15136585}. |
| Mouse PG classification | NA |
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