| Gene Information | |
|---|---|
| Gene Name | BMAL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 636 |
| Protein Names | Basic helix-loop-helix ARNT-like protein 2 (Aryl hydrocarbon receptor nuclear translocator-like protein 2) (Basic-helix-loop-helix-PAS protein MOP9) (Brain and muscle ARNT-like 2) (CYCLE-like factor) (CLIF) (Class E basic helix-loop-helix protein 6) (bHLHe6) (Member of PAS protein 9) (PAS domain-containing protein 9) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000029153 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8WYA1 |
| Gene Card | ARNTL2 |
| Uniprot ID | Q8WYA1 |
| Pfam | PF00010; PF00989 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | BMAL1 |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in fetal brain. Highly expressed in brain and placenta. Lower levels in heart, liver, thymus, kidney and lung. Located to endothelial cells and neuronal cells of the suprachiasmatic nucleus (SCN). Also detected in endothelial cells of the heart, lung and kidney. In the brain, specifically expressed in the thalamus, hippocampus and amygdala. {ECO:0000269|PubMed:10864977, ECO:0000269|PubMed:10964693, ECO:0000269|PubMed:11018023}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KDK (NMR - ) |
| DBSNP | rs1037921 rs11049005 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:10964693}. |
| Mouse PG classification | NA |
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