| Gene Information | |
|---|---|
| Gene Name | PRDM5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 630 |
| Protein Names | PR domain zinc finger protein 5 (EC 2.1.1.-) (PR domain-containing protein 5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000138738 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9NQX1 |
| Gene Card | PRDM5 |
| Uniprot ID | Q9NQX1 |
| Pfam | PF00096 |
| In ASD | no |
| Allosteric Prediction | no (-0.987436179) |
| Ortholog in Animals | Alpaca_ PRDM5 ( ortholog_one2one ) GuineaPig_ PRDM5 ( ortholog_one2one ) Macaque_ PRDM5 ( ortholog_one2one ) Mouse_ Prdm5 ( ortholog_one2one ) Pig_ PRDM5 ( ortholog_one2one ) Rat_ Prdm5 ( ortholog_one2one ) Rabbit_ PRDM5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ZNF850, ZNF358, ZNF668, ZNF579 |
| Tissue | NA |
| Tissue Specificity | Widely expressed with highest levels in colon and ovary. Tends to be silenced in breast, colorectal, gastric and liver cancer tissues. {ECO:0000269|PubMed:15077163, ECO:0000269|PubMed:17699856}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6XAZ (X-ray 1.70A ) |
| DBSNP | rs387907111 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:15077163, ECO:0000269|PubMed:17636019}. |
| Mouse PG classification | LPG |
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