| Gene Information | |
|---|---|
| Gene Name | PDLIM2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 352 |
| Protein Names | PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000120913 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96JY6 |
| Gene Card | PDLIM2 |
| Uniprot ID | Q96JY6 |
| Pfam | PF15936; PF00412; PF00595 |
| In ASD | no |
| Allosteric Prediction | no (-1.065176049) |
| Ortholog in Animals | Alpaca_ PDLIM2 ( ortholog_one2one ) Dog_ PDLIM2 ( ortholog_one2one ) Macaque_ PDLIM2 ( ortholog_one2one ) Mouse_ Pdlim2 ( ortholog_one2one ) Pig_ PDLIM2 ( ortholog_one2one ) Rat_ Pdlim2 ( ortholog_one2one ) Rabbit_ PDLIM2 ( ortholog_one2one ) |
| Ohnologs | PDLIM1, PDLIM4 |
| Paralogs | PDLIM1, PDLIM3, LDB3, PDLIM5, PDLIM7, PDLIM4, PRICKLE4 |
| Tissue | spleen |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2PA1 (X-ray 1.70A ) 3PDV (X-ray 2.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15659642}. Nucleus {ECO:0000269|PubMed:15659642}. Note=May be partially nuclear.; [Isoform 1]: Cytoplasm, cytoskeleton. Note=Colocalizes with beta-1 integrin (ITGB1) and alpha-actinin but not with paxillin (PXN).; [Isoform 2]: Cytoplasm, cytoskeleton.; [Isoform 3]: Nucleus. |
| Mouse PG classification | NA |
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