| Gene Information | |
|---|---|
| Gene Name | UBA7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1012 |
| Protein Names | Ubiquitin-like modifier-activating enzyme 7 (Ubiquitin-activating enzyme 7) (D8) (Ubiquitin-activating enzyme E1 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000182179 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P41226 |
| Gene Card | UBA7 |
| Uniprot ID | P41226 |
| Pfam | PF16191; PF16190; PF09358; PF00899; PF10585 |
| In ASD | no |
| Allosteric Prediction | no (-0.685848058) |
| Ortholog in Animals | Alpaca_ UBA7 ( ortholog_one2one ) Dog_ CDHR4 ( ortholog_one2one ) GuineaPig_ UBA7 ( ortholog_one2one ) Macaque_ UBA7 ( ortholog_one2one ) Mouse_ Uba7 ( ortholog_one2one ) Pig_ UBA7 ( ortholog_one2one ) Rat_ Uba7 ( ortholog_one2one ) Rabbit_ UBA7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | UBA3, NAE1, UBA6, UBA2, UBA1, UBA5, MOCS3, ATG7, SAE1 |
| Tissue | NA |
| Tissue Specificity | Expressed in a variety of normal and tumor cell types, but is reduced in lung cancer cell lines. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11928913 rs2230149 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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