| Gene Information | |
|---|---|
| Gene Name | ASCL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 236 |
| Protein Names | Achaete-scute homolog 1 (ASH-1) (hASH1) (Class A basic helix-loop-helix protein 46) (bHLHa46) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000139352 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P50553 |
| Gene Card | ASCL1 |
| Uniprot ID | P50553 |
| Pfam | PF00010 |
| In ASD | no |
| Allosteric Prediction | no (-0.921418713) |
| Ortholog in Animals | Alpaca_ ASCL1 ( ortholog_one2one ) Dog_ ASCL1 ( ortholog_one2one ) GuineaPig_ ASCL1 ( ortholog_one2one ) Macaque_ ASCL1 ( ortholog_one2one ) Mouse_ Ascl1 ( ortholog_one2one ) Pig_ ASCL1 ( ortholog_one2one ) Rat_ Ascl1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ASCL2, ASCL4, ASCL5, ASCL3 |
| Tissue | brain, amygdala, pituitary.gland |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1803157 |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:Q02067}. |
| Mouse PG classification | NA |
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