| Gene Information | |
|---|---|
| Gene Name | POR |
| Organism | Homo sapiens (Human) |
| Gene Length | 677 |
| Protein Names | NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4) |
| Target Name | cytochrome p450 reductase |
| Target Type | Discontinued target |
| Gene Age | >4290 ( ENSG00000127948 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P16435 |
| Gene Card | POR |
| Uniprot ID | P16435 |
| Pfam | PF00667; PF00258; PF00175 |
| In ASD | no |
| Allosteric Prediction | yes (0.745925862) |
| Ortholog in Animals | Alpaca_ POR ( ortholog_one2many ) Dog_ POR ( ortholog_one2one ) GuineaPig_ POR ( ortholog_one2one ) Macaque_ POR ( ortholog_one2one ) Mouse_ Por ( ortholog_one2one ) Pig_ POR ( ortholog_one2one ) Rat_ Por ( ortholog_one2one ) Rabbit_ POR ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MTRR, NOS1, NDOR1, NOS2, NOS3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1B1C (X-ray 1.93A ) 3FJO (X-ray 2.50A ) 3QE2 (X-ray 1.75A ) 3QFC (X-ray 1.80A ) 3QFR (X-ray 2.40A ) 3QFS (X-ray 1.40A ) 3QFT (X-ray 1.40A ) 5EMN (X-ray 2.20A ) 5FA6 (X-ray 2.30A ) |
| DBSNP | rs72552771 rs17853284 rs41299514 rs121912974 rs28931608 rs28931606 rs1057868 rs72552772 rs72552772 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000255|HAMAP-Rule:MF_03212}; Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_03212}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_03212}. |
| Mouse PG classification | LPG |
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