| Gene Information | |
|---|---|
| Gene Name | LRPAP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 357 |
| Protein Names | Alpha-2-macroglobulin receptor-associated protein (Alpha-2-MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000163956 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P30533 |
| Gene Card | LRPAP1 |
| Uniprot ID | P30533 |
| Pfam | PF06401; PF06400 |
| In ASD | no |
| Allosteric Prediction | no (-0.012599861) |
| Ortholog in Animals | Alpaca_ LRPAP1 ( ortholog_one2one ) Dog_ LRPAP1 ( ortholog_one2one ) GuineaPig_ LRPAP1 ( ortholog_one2one ) Macaque_ LRPAP1 ( ortholog_one2one ) Mouse_ Lrpap1 ( ortholog_one2one ) Pig_ LRPAP1 ( ortholog_one2one ) Rat_ Lrpap1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1LRE (NMR - ) 1NRE (NMR - ) 1OP1 (NMR - ) 1OV2 (NMR - ) 2FCW (X-ray 1.26A ) 2FTU (NMR - ) 2FYL (NMR - ) 2P01 (NMR - ) 2P03 (NMR - ) |
| DBSNP | rs2228158 rs1800493 |
| Subcellular location [CC] | Rough endoplasmic reticulum lumen {ECO:0000269|PubMed:7774585}. Endoplasmic reticulum-Golgi intermediate compartment lumen {ECO:0000269|PubMed:7774585}. Golgi apparatus, cis-Golgi network {ECO:0000269|PubMed:7774585}. Golgi apparatus lumen {ECO:0000269|PubMed:7774585}. Endosome lumen {ECO:0000269|PubMed:7774585}. Cell surface {ECO:0000269|PubMed:11384978}. Note=May be associated with receptors at the cell surface. {ECO:0000269|PubMed:11384978}. |
| Mouse PG classification | LPG |
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