Gene Information
Gene NamePRSS27
OrganismHomo sapiens (Human)
Gene Length290
Protein NamesSerine protease 27 (EC 3.4.21.-) (Marapsin) (Pancreasin)
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000172382 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9BQR3
Gene CardPRSS27
Uniprot IDQ9BQR3
PfamPF00089
In ASDno
Allosteric Predictionno (-1.11104315)
Ortholog in AnimalsAlpaca_ PRSS27 ( ortholog_one2many )
GuineaPig_ PRSS27 ( ortholog_one2one )
Macaque_ PRSS27 ( ortholog_one2one )
Mouse_ Prss27 ( ortholog_one2one )
Pig_ PRSS27 ( ortholog_one2one )
Rat_ Prss27 ( ortholog_one2one )
Rabbit_ PRSS27 ( ortholog_one2one )
OhnologsTMPRSS6, PRSS8, TMPRSS11B
ParalogsOVCH1, PLAT, PRSS48, PLGLB1, PLGLB2, PLG, TMPRSS12, GZMM, KLK15, PRSS37, PRSS33, PRSS57, PRSS50, KLK9
Tissueesophagus, tongue, esophagus.mucosa
Tissue SpecificityExpressed predominantly in the pancreas. {ECO:0000269|PubMed:12441343}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Secreted.
Mouse PG classificationNA
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