Gene Information
Gene NameDLC1
OrganismHomo sapiens (Human)
Gene Length1755
Protein NamesDeleted in lung and esophageal cancer protein 1 (Deleted in lung cancer protein 1) (DLC-1)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000164741 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9Y238
Gene CardDLEC1
Uniprot IDQ9Y238
PfamNA
In ASDno
Allosteric Predictionno (-0.230106252)
Ortholog in AnimalsAlpaca_ DLC1 ( ortholog_one2one )
Dog_ DLC1 ( ortholog_one2one )
GuineaPig_ DLC1 ( ortholog_one2one )
Macaque_ DLC1 ( ortholog_one2one )
Mouse_ Dlc1 ( ortholog_one2one )
Pig_ DLC1 ( ortholog_one2one )
Rat_ Dlc1 ( ortholog_one2one )
Rabbit_ DLC1 ( ortholog_one2one )
OhnologsSTARD8, STARD13
ParalogsSTARD8, STARD13
TissueNA
Tissue SpecificityExpressed in all tissues examined. Expression is highest in prostate and testis. {ECO:0000269|PubMed:10213508}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs7625806  rs34012183  rs36012922  rs9840172  rs9810085 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:10213508, ECO:0000269|PubMed:33144677}.
Mouse PG classificationLPG
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