| Gene Information | |
|---|---|
| Gene Name | BCAT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 392 |
| Protein Names | Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT(m)) (EC 2.6.1.42) (Placental protein 18) (PP18) |
| Target Name | branched-chain-amino-acid transaminase 2 |
| Target Type | Literature-reported target |
| Gene Age | >4290 ( ENSG00000105552 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O15382 |
| Gene Card | BCAT2 |
| Uniprot ID | O15382 |
| Pfam | PF01063 |
| In ASD | no |
| Allosteric Prediction | no (-0.173308598) |
| Ortholog in Animals | Alpaca_ BCAT2 ( ortholog_one2one ) Dog_ BCAT2 ( ortholog_one2one ) GuineaPig_ BCAT2 ( ortholog_one2one ) Macaque_ BCAT2 ( ortholog_one2one ) Mouse_ Bcat2 ( ortholog_one2one ) Pig_ BCAT2 ( ortholog_one2one ) Rat_ Bcat2 ( ortholog_one2one ) Rabbit_ BCAT2 ( ortholog_one2one ) |
| Ohnologs | BCAT1 |
| Paralogs | BCAT1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:11170829}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.026087(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1EKF (X-ray 1.95A ) 1EKP (X-ray 2.50A ) 1EKV (X-ray 2.25A ) 1KT8 (X-ray 1.90A ) 1KTA (X-ray 1.90A ) 2A1H (X-ray 1.80A ) 2HDK (X-ray 2.40A ) 2HG8 (X-ray 1.80A ) 2HGW (X-ray 1.98A ) 2HGX (X-ray 1.80A ) 2HHF (X-ray 1.80A ) 5BWR (X-ray 2.20A ) 5BWT (X-ray 2.20A ) 5BWU (X-ray 2.17A ) 5BWV (X-ray 1.86A ) 5BWW (X-ray 1.82A ) 5BWX (X-ray 1.70A ) 5CR5 (X-ray 1.61A ) 5HNE (X-ray 2.04A ) 5I5S (X-ray 2.06A ) 5I5T (X-ray 2.31A ) 5I5U (X-ray 2.40A ) 5I5V (X-ray 1.94A ) 5I5W (X-ray 2.40A ) 5I5X (X-ray 1.65A ) 5I5Y (X-ray 1.81A ) 5I60 (X-ray 2.12A ) 5MPR (X-ray 1.60A ) 6PRX (X-ray 3.25A ) |
| DBSNP | rs749866079 rs11548193 rs767653663 |
| Subcellular location [CC] | Mitochondrion {ECO:0000250|UniProtKB:O35854}. |
| Mouse PG classification | NA |
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