| Gene Information | |
|---|---|
| Gene Name | PPY |
| Organism | Homo sapiens (Human) |
| Gene Length | 95 |
| Protein Names | Pancreatic prohormone (Pancreatic polypeptide) (PP) (Obinepitide) [Cleaved into: Pancreatic hormone (PH); Pancreatic icosapeptide (PI)] |
| Target Name | pancreatic hormone |
| Target Type | Clinical trial target |
| Gene Age | 101 ( ENSG00000108849 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P01298 |
| Gene Card | PPY |
| Uniprot ID | P01298 |
| Pfam | PF00159 |
| In ASD | no |
| Allosteric Prediction | yes (0.101862829) |
| Ortholog in Animals | Alpaca_ PPY ( ortholog_one2one ) Dog_ PPY ( ortholog_one2one ) Macaque_ PPY ( ortholog_one2one ) Mouse_ Ppy ( ortholog_one2one ) Pig_ PPY ( ortholog_one2one ) Rat_ Ppy ( ortholog_one2one ) Rabbit_ PPY ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NPY, PYY |
| Tissue | pancreas |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1TZ4 (NMR - ) 1TZ5 (NMR - ) 7X9C (EM 3.00A ) |
| DBSNP | rs7215698 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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