| Gene Information | |
|---|---|
| Gene Name | PPP5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 499 |
| Protein Names | Serine/threonine-protein phosphatase 5 (PP5) (EC 3.1.3.16) (Protein phosphatase T) (PP-T) (PPT) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P53041 |
| Gene Card | PPP5C |
| Uniprot ID | P53041 |
| Pfam | PF00149; PF08321; PF00515 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:15546861}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1A17 (X-ray 2.45A ) 1S95 (X-ray 1.60A ) 1WAO (X-ray 2.90A ) 2BUG (NMR - ) 3H60 (X-ray 2.00A ) 3H61 (X-ray 1.45A ) 3H62 (X-ray 1.40A ) 3H63 (X-ray 1.30A ) 3H64 (X-ray 1.90A ) 3H66 (X-ray 2.59A ) 3H67 (X-ray 1.65A ) 3H68 (X-ray 1.50A ) 3H69 (X-ray 2.10A ) 4ZVZ (X-ray 2.00A ) 4ZX2 (X-ray 1.23A ) 5HPE (X-ray 2.27A ) 5UI1 (X-ray 1.96A ) 5WG8 (X-ray 1.65A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:15383005}. Cytoplasm {ECO:0000269|PubMed:15383005, ECO:0000269|PubMed:19948726}. Cell membrane {ECO:0000269|PubMed:19948726}. Note=Predominantly nuclear (PubMed:15383005). But also present in the cytoplasm (PubMed:15383005). Translocates from the cytoplasm to the plasma membrane in a RAC1-dependent manner (PubMed:19948726). {ECO:0000269|PubMed:15383005, ECO:0000269|PubMed:19948726}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |