| Gene Information | |
|---|---|
| Gene Name | PPP4R3B |
| Organism | Homo sapiens (Human) |
| Gene Length | 849 |
| Protein Names | Serine/threonine-protein phosphatase 4 regulatory subunit 3B (SMEK homolog 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000275052 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q5MIZ7 |
| Gene Card | PPP4R3B |
| Uniprot ID | Q5MIZ7 |
| Pfam | PF04802 |
| In ASD | no |
| Allosteric Prediction | no (-0.233450217) |
| Ortholog in Animals | Alpaca_ PPP4R3B ( ortholog_one2one ) Dog_ PPP4R3B ( ortholog_one2one ) GuineaPig_ PPP4R3B ( ortholog_one2one ) Macaque_ PPP4R3B ( ortholog_one2one ) Mouse_ Ppp4r3b ( ortholog_one2one ) Pig_ PPP4R3B ( ortholog_one2one ) Rat_ Ppp4r3b ( ortholog_one2one ) Rabbit_ PPP4R3B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PPP4R3C, PPP4R3A |
| Tissue | NA |
| Tissue Specificity | Moderately expressed in tissues and specific brain regions examined. {ECO:0000269|PubMed:10718198}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001990(Rat);0.022222(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34999684 rs2903704 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:18487071}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:18487071}. Nucleus {ECO:0000269|PubMed:18487071}. Note=In interphase localized in the cytoplasm and (with higher levels) the nucleus. During metaphase located in pericentriolar regions. |
| Mouse PG classification | NA |
| click here to return to the previous page | |