| Gene Information | |
|---|---|
| Gene Name | PPP4R3A |
| Organism | Homo sapiens (Human) |
| Gene Length | 833 |
| Protein Names | Serine/threonine-protein phosphatase 4 regulatory subunit 3A (SMEK homolog 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000100796 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6IN85 |
| Gene Card | PPP4R3A |
| Uniprot ID | Q6IN85 |
| Pfam | PF04802 |
| In ASD | no |
| Allosteric Prediction | no (-0.251753971) |
| Ortholog in Animals | Alpaca_ PPP4R3A ( ortholog_one2one ) Dog_ PPP4R3A ( ortholog_one2one ) GuineaPig_ PPP4R3A ( ortholog_one2one ) Macaque_ PPP4R3A ( ortholog_one2one ) Mouse_ Ppp4r3a ( ortholog_one2one ) Pig_ PPP4R3A ( ortholog_one2one ) Rat_ Ppp4r3a ( ortholog_one2one ) Rabbit_ PPP4R3A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PPP4R3C, PPP4R3B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.026667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6R8I (X-ray 1.52A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:18487071}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:18487071}. Nucleus {ECO:0000269|PubMed:18487071}. Note=In interphase localized in the cytoplasm and in the nucleus (with higher levels). During metaphase located in pericentriolar regions. |
| Mouse PG classification | NA |
| click here to return to the previous page | |